Title : Renalase does not catalyze the oxidation of catecholamines.

Pub. Date : 2015 Aug 1

PMID : 26049000






3 Functional Relationships(s)
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1 Renalase does not catalyze the oxidation of catecholamines. Catecholamines renalase, FAD dependent amine oxidase Homo sapiens
2 It is widely accepted that the function of human renalase is to oxidize catecholamines in blood. Catecholamines renalase, FAD dependent amine oxidase Homo sapiens
3 Using time-dependent spectrophotometry we show that the renalase FAD cofactor spectrum is unresponsive to added catecholamines, that adrenochromes are not observed to accumulate in the presence of renalase and that the kinetics of single turnover reactions with 6-dihydroNAD are unaltered by the addition of catecholamines. Catecholamines renalase, FAD dependent amine oxidase Homo sapiens