Pub. Date : 2015
PMID : 26045989
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of GnT-V and its GlcNAc-beta1-6 oligosaccharides by-product together with Con-A binding sugars were assessed immunohistochemically on tissue microarrays of 16 normal brain and 159 tissue samples of astrocytomas of variable grades and histology. | 2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | Homo sapiens |
| 2 | Although tissues of both grade I astrocytomas and normal brain showed considerably higher GnT-V expression, GlcNAc-beta1-6 expression was significantly high only in tissues of grade I astrocytomas (p < 0.001), which is attributable to elevated levels of the precursor Con-A binding sugar moieties (p < 0.001). | 2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | Homo sapiens |
| 3 | The activity of GnT-V enzyme was found to be dependent on the degree of glioma pathogenesis, as the GlcNAc-beta1-6 branched expression diminished with every progressive grade of glioma, reaching minimum in glioblastoma (p < 0.001). | 2-acetamido-2-deoxy-4-O-(beta-2-acetamid-2-deoxyglucopyranosyl)glucopyranose | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | Homo sapiens |