Title : Clinicopathological correlates of adrenal Cushing's syndrome.

Pub. Date : 2015 Jun

PMID : 26045561






1 Functional Relationships(s)
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1 Recently, important mechanisms underlying the pathogenesis of adrenal hypercortisolism have been elucidated with the discovery of mutations in cyclic AMP signalling (PRKACA, PRKAR1A, GNAS, PDE11A, PDE8B), armadillo repeat containing 5 gene (ARMC5) a putative tumour suppressor gene, aberrant G-protein-coupled receptors, and intra-adrenal secretion of ACTH. Cyclic AMP proopiomelanocortin Homo sapiens