Title : Progesterone metabolites as farnesoid X receptor inhibitors.

Pub. Date : 2015

PMID : 26045261






2 Functional Relationships(s)
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1 Progesterone metabolites as farnesoid X receptor inhibitors. Progesterone xenotropic and polytropic retrovirus receptor 1 Homo sapiens
2 Studies using human and rodent specimens have shown that sulfated metabolites of progesterone competitively inhibit bile acid homeostasis pathways by functioning as partial agonists of farnesoid X receptor (FXR). Progesterone xenotropic and polytropic retrovirus receptor 1 Homo sapiens