Title : Effects of chronic inhibition of GABA synthesis on attention and impulse control.

Pub. Date : 2015 Aug

PMID : 26044967






2 Functional Relationships(s)
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1 In schizophrenia for example, changes in GABA neurons [reduced expression of glutamic acid decarboxylase (GAD), parvalbumin (PV) and the GABA reuptake transporter (GAT1)] suggest reduced cortical GABA synthesis and release; these changes are hypothesized to cause the cognitive deficits observed in this disorder. gamma-Aminobutyric Acid parvalbumin Rattus norvegicus
2 In schizophrenia for example, changes in GABA neurons [reduced expression of glutamic acid decarboxylase (GAD), parvalbumin (PV) and the GABA reuptake transporter (GAT1)] suggest reduced cortical GABA synthesis and release; these changes are hypothesized to cause the cognitive deficits observed in this disorder. gamma-Aminobutyric Acid parvalbumin Rattus norvegicus