Title : The presence of prolines in the flanking region of an immunodominant HIV-2 gag epitope influences the quality and quantity of the epitope generated.

Pub. Date : 2015 Aug

PMID : 26018465






2 Functional Relationships(s)
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1 Previously, we showed that the magnitude of the HIV-2 gag-specific T-cell response is inversely correlated with plasma viral load, particularly when responses are directed against an epitope, 165 DRFYKSLRA173 , within the highly conserved Major Homology Region of gag-p26. Glycosaminoglycans transmembrane p24 trafficking protein 3 Homo sapiens
2 We also showed that the presence of three proline residues, at positions 119, 159 and 178 of gag-p26, was significantly correlated with low viral load. Glycosaminoglycans transmembrane p24 trafficking protein 3 Homo sapiens