Pub. Date : 2015
PMID : 26015807
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | It also revealed overexpression of the ATM/p53/p21 pathway, which is activated in response to DNA damage and induces cell cycle arrest in thiopurine resistant LCLs. | 2-mercaptopyrazine | tumor protein p53 | Homo sapiens |
| 2 | Furthermore, overexpression of the p53 target gene TNFRSF10D or the negative cell cycle regulator CCNG2 induces cell cycle arrest and may also contribute to thiopurine resistance. | 2-mercaptopyrazine | tumor protein p53 | Homo sapiens |