Pub. Date : 2015 Sep
PMID : 26014912
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The collective nuclear migration of p53 and phosphorylated S473 of Akt during ellipticine-mediated apoptosis in human lung epithelial cancer cells. | ellipticine | tumor protein p53 | Homo sapiens |
| 2 | In addition, ellipticine induced cytotoxicity in p53-null H1299 cells with stable expression of ectopic p53. | ellipticine | tumor protein p53 | Homo sapiens |
| 3 | In addition, ellipticine induced cytotoxicity in p53-null H1299 cells with stable expression of ectopic p53. | ellipticine | tumor protein p53 | Homo sapiens |
| 4 | In this work, we further demonstrated that dominant-negative Akt (S473A) or p53 shRNA inhibited ellipticine-mediated translocalization of p53 and Akt and attenuated apoptotic cell death in A549 cells. | ellipticine | tumor protein p53 | Homo sapiens |
| 5 | In this work, we further demonstrated that dominant-negative Akt (S473A) or p53 shRNA inhibited ellipticine-mediated translocalization of p53 and Akt and attenuated apoptotic cell death in A549 cells. | ellipticine | tumor protein p53 | Homo sapiens |
| 6 | The presence of p53 predates ellipticine-mediated apoptotic cell death, assists in nucleus translocation of phosphorylated Akt and activation of autophagy pathway. | ellipticine | tumor protein p53 | Homo sapiens |