Title : Metabotropic glutamate receptor-mediated cyclic ADP ribose signalling.

Pub. Date : 2015 Jun

PMID : 26009183






1 Functional Relationships(s)
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1 A prime candidate for mediating this coupling between I-mGluR activation and RyR opening is cyclic ADP ribose (cADPR) and, indeed, several of these PLC-/IP3-independent I-mGluR-evoked calcium signals have now been shown to be mediated wholly or partly by cADPR-evoked activation of RyRs. Calcium ryanodine receptor 2 Homo sapiens