Title : Reductive carboxylation and 2-hydroxyglutarate formation by wild-type IDH2 in breast carcinoma cells.

Pub. Date : 2015 Aug

PMID : 26007236






1 Functional Relationships(s)
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Protein Name
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1 Mutant IDH1/IDH2 enzymes were reported to form an oncometabolite r-2-hydroxyglutarate (2HG), further strengthening malignancy. r-2-hydroxyglutarate isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens