Title : Regulatory mechanism of the gastric hyperemic response following barrier disruption: roles of cyclooxygenase-1, the prostaglandin E2/EP1 receptor and sensory neurons.

Pub. Date : 2015

PMID : 26004410






1 Functional Relationships(s)
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1 Thus, endogenous PGE2 produced by COX-1 plays a role in the gastric hyperemic response following barrier disruption of the stomach by interacting with capsaicin-sensitive afferent neurons, mainly through EP1 receptors, and facilitating the GMBF response to acid back-diffusion. Dinoprostone prostaglandin E receptor 1 (subtype EP1) Mus musculus