Pub. Date : 2015 Oct
PMID : 25989700
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rapamycin ameliorates the CTLA4-Ig-mediated defect in CD8(+) T cell immunity during gammaherpesvirus infection. | Sirolimus | cytotoxic T-lymphocyte associated protein 4 | Homo sapiens |
| 2 | However, the addition of rapamycin to the CTLA4-Ig regimen was able to quantitatively and qualitatively restore the antigen-specific CD8(+) T cell response to the virus. | Sirolimus | cytotoxic T-lymphocyte associated protein 4 | Homo sapiens |
| 3 | This improvement was physiologically relevant, in that CTLA4-Ig treated animals exhibited a greater viral burden following infection that was reduced to levels observed in untreated immunocompetent animals by the addition of rapamycin. | Sirolimus | cytotoxic T-lymphocyte associated protein 4 | Homo sapiens |