Title : Dependence of the rate of thrombin/antithrombin III reaction upon the turnover rate of a catalytic amount of heparin.

Pub. Date : 1989 Aug

PMID : 2598315






3 Functional Relationships(s)
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1 However, this accelerative activity was significantly lower than that induced by heparin with high affinity for AT III (HA-heparin), probably due to the formation of the binary complexes of HA-heparin-AT III as well as that composed of thrombin and heparin with low affinity for AT III (LA-heparin). la-heparin serpin family C member 1 Homo sapiens
2 LA-heparin and dextran sulfate (DS) were also found to accelerate the thrombin/AT III reaction rate, but neither substance catalyzed the formation of the complex in the presence of 0.1 M NaCl at pH 7.4. la-heparin serpin family C member 1 Homo sapiens
3 LA-heparin was also confirmed to compete with HA-heparin for enhancement of the thrombin/AT III reaction. la-heparin serpin family C member 1 Homo sapiens