Title : Intraperitoneal therapy with interferon-alpha in CAPD patients with relapsing bacterial peritonitis.

Pub. Date : 1989 Jul-Sep

PMID : 2597493






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1 Because previous studies showed that interferon-alpha (IFN-alpha) is able to increase in vitro the number of PM0 IgG FcR in CAPD patients with relapsing bacterial peritonitis, the authors studied the in vivo effects of IP administration of IFN-alpha (1,000 IU daily in the overnight exchange for 12 months) on: PM0 superoxide generation; PM0 bacterial killing; PM0 IgG FcR; the number of bacteria in the PM0 cytoplasm; and peritonitis relapses in these patients. Superoxides interferon alpha 1 Homo sapiens