Title : Prefrontal Cortical Kappa Opioid Receptors Attenuate Responses to Amygdala Inputs.

Pub. Date : 2015 Dec

PMID : 25971593






2 Functional Relationships(s)
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1 Intra-mPFC U69,593 inhibited electrical and optogenetic BLA-evoked synaptic responses, an effect blocked by the KOR antagonist nor-BNI. norbinaltorphimine opioid receptor kappa 1 Homo sapiens
2 Bilateral intra-mPFC injection of the KOR antagonist nor-BNI increased center time in the open field test, suggesting an anxiolytic effect. norbinaltorphimine opioid receptor kappa 1 Homo sapiens