Title : Receptor- and phorbol-ester-mediated redistribution of protein kinase C in human platelets. Evidence that aggregation promotes degradation of protein kinase C.

Pub. Date : 1989 Nov 1

PMID : 2597139






1 Functional Relationships(s)
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1 In stirred platelets, total and specific inhibition of PMA-induced aggregation by a fibrinogen-derived peptide (RGDS, i.e. Arg-Gly-Asp-Ser) promoted maximal increases in membrane-associated PKC in the presence of PMA and completely prevented the loss in cellular activity. Arginine ral guanine nucleotide dissociation stimulator Homo sapiens