Title : Effects of LY117018 (a SERM analog of raloxifene) on tumor suppressor proteins and proliferation of breast cancer cells.

Pub. Date : 2010 Aug 1

PMID : 25961194






1 Functional Relationships(s)
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1 We have previously shown that presence of estradiol (E2) in the growth medium causes (i) proliferation of T47D breast cancer cells, (ii) elevation of p53 levels, and (iii) hyperphos-phorylation of retinoblastoma protein (pRb). Estradiol tumor protein p53 Homo sapiens