Title : Metformin Causes G1-Phase Arrest via Down-Regulation of MiR-221 and Enhances TRAIL Sensitivity through DR5 Up-Regulation in Pancreatic Cancer Cells.

Pub. Date : 2015

PMID : 25955843






1 Functional Relationships(s)
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1 Moreover, we showed that the down-regulation of miR-221 by metformin caused G1-phase arrest via the up-regulation of p27, one of the direct targets of miR-221. Metformin interferon alpha inducible protein 27 Homo sapiens