Pub. Date : 2015 Jul
PMID : 25954928
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, we report that miR-153 are negative regulators of SET7 and ZEB2, miR-153 regulates SET7/ZEB2 expression and promotes SET7/ZEB2 mRNA degradation. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 2 | In the present study, we report that miR-153 are negative regulators of SET7 and ZEB2, miR-153 regulates SET7/ZEB2 expression and promotes SET7/ZEB2 mRNA degradation. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 3 | In the present study, we report that miR-153 are negative regulators of SET7 and ZEB2, miR-153 regulates SET7/ZEB2 expression and promotes SET7/ZEB2 mRNA degradation. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 4 | Further, confirmed by reporter assays, SET7/ZEB2 are downstream targets of miR-153 directly bound to the 3" untranslated region (3"-UTR). | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 5 | SET7 and ZEB2 are negatively correlated with miR-153 expression in human ovarian cancer and indicated a worse survival. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 6 | Based on our results miR-153 inhibits proliferation and suppresses EMT and the invasive potential of ovarian cancer cells through downregulation of SET7 and ZEB2, supporting the pursuit of miR-153 as a potential target for ovarian cancer intervention. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |
| 7 | Based on our results miR-153 inhibits proliferation and suppresses EMT and the invasive potential of ovarian cancer cells through downregulation of SET7 and ZEB2, supporting the pursuit of miR-153 as a potential target for ovarian cancer intervention. | mir-153 | zinc finger E-box binding homeobox 2 | Homo sapiens |