Title : [Metformin Influences the Effect of Adipocytes on Leukemia Cell Chemoresistance through Regulation of Adipogenesis].

Pub. Date : 2015 Apr

PMID : 25948182






1 Functional Relationships(s)
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1 RESULTS: The metformin lowered the OD value, and the expression levels of both adipogenic genes C/EBPalpha and FABP4 were lower than those of controls, while the expression level of PPARgamma mRNA was not significantly changed, the apoptosis rate of leukemia cells co-caltured with metformin-treated adipocytes was higher than that of co-cultured cells without metformin treatment. Metformin fatty acid binding protein 4 Homo sapiens