Title : DNA methylation and gene expression profiles show novel regulatory pathways in hepatocellular carcinoma.

Pub. Date : 2015

PMID : 25945129






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Notably, promoter DNA methylation emerged as a novel regulatory mechanism for the transcriptional repression of genes controlling the retinol metabolism (ADH1A, ADH1B, ADH6, CYP3A43, CYP4A22, RDH16), iron homeostasis (HAMP), one-carbon metabolism (SHMT1), and genes with a putative, newly identified function as tumor suppressors (FAM107A, IGFALS, MT1G, MT1H, RNF180). Vitamin A alcohol dehydrogenase 6 (class V) Homo sapiens