Title : Irreversible dual inhibitory mode: the novel Btk inhibitor PLS-123 demonstrates promising anti-tumor activity in human B-cell lymphoma.

Pub. Date : 2015 Jun 20

PMID : 25944695






1 Functional Relationships(s)
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1 The phosphorylation of BCR downstream activating AKT/mTOR and MAPK signal pathways was also more significantly reduced after treatment with PLS-123 than ibrutinib. ibrutinib AKT serine/threonine kinase 1 Homo sapiens