Title : Salvianolic acid A attenuates TNF-α- and D-GalN-induced ER stress-mediated and mitochondrial-dependent apoptosis by modulating Bax/Bcl-2 ratio and calcium release in hepatocyte LO2 cells.

Pub. Date : 2015 Aug

PMID : 25943027






2 Functional Relationships(s)
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1 Furthermore, the decreased levels of Bax/Bcl-2 ratio and calcium release were measured in Sal A-treated cells. salvianolic acid BCL2 associated X, apoptosis regulator Homo sapiens
2 In summary, Sal A attenuates TNF-alpha- and D-GalN-induced both ER stress and mitochondrial-dependent apoptosis by suppression of Bax/Bcl-2 ratio and prevention of calcium release, which support the notion that Sal A could be developed into a novel hepatic protectant. salvianolic acid BCL2 associated X, apoptosis regulator Homo sapiens