Title : Celastrol inhibits inflammatory stimuli-induced neutrophil extracellular trap formation.

Pub. Date : 2015

PMID : 25941817






2 Functional Relationships(s)
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1 We found that celastrol can completely inhibit neutrophil oxidative burst and NET formation induced by tumor necrosis factor alpha (TNFalpha) with an IC50 of 0.34 microM and by ovalbumin:anti-ovalbumin immune complexes (Ova IC) with an IC50 of 1.53 microM. celastrol tumor necrosis factor Homo sapiens
2 We found that celastrol can completely inhibit neutrophil oxidative burst and NET formation induced by tumor necrosis factor alpha (TNFalpha) with an IC50 of 0.34 microM and by ovalbumin:anti-ovalbumin immune complexes (Ova IC) with an IC50 of 1.53 microM. celastrol tumor necrosis factor Homo sapiens