Title : The lidocaine metabolite N-ethylglycine has antinociceptive effects in experimental inflammatory and neuropathic pain.

Pub. Date : 2015 Sep

PMID : 25932687






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling. Glycine solute carrier family 6 member 9 Homo sapiens
2 Glycine transporter 1 (GlyT1) plays a crucial role in regulating extracellular glycine concentrations and might thereby constitute a new drug target for the modulation of glycinergic inhibition in pain signaling. Glycine solute carrier family 6 member 9 Homo sapiens
3 We have shown previously that the lidocaine metabolite N-ethylglycine (EG) reduces GlyT1-dependent glycine uptake by functioning as an artificial substrate for this transporter. Glycine solute carrier family 6 member 9 Homo sapiens