Title : Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling.

Pub. Date : 2015

PMID : 25931810






1 Functional Relationships(s)
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1 The results showed that paclitaxel treatment resulted in a dose- and time-dependent decrease in tyrosine-phosphorylated STAT3, and inhibited the expression of fibronectin, alpha-smooth muscle actin (alpha-SMA), and collagen I in cultured NRK-49F cells. Tyrosine signal transducer and activator of transcription 3 Rattus norvegicus