Title : Coexpression of hyperactivated AKT1 with additional genes activated in leukemia drives hematopoietic progenitor cells to cell cycle block and apoptosis.

Pub. Date : 2015 Jul

PMID : 25931014






1 Functional Relationships(s)
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1 Although cells expressing hyperactivated AKT1 displayed higher levels of reactive oxygen species both in vitro and in vivo, the addition of the antioxidant N-acetyl-L-cysteine significantly reduced apoptosis. Acetylcysteine thymoma viral proto-oncogene 1 Mus musculus