Title : Endogenous VSIG4 negatively regulates the helper T cell-mediated antibody response.

Pub. Date : 2015 Jun

PMID : 25929804






1 Functional Relationships(s)
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1 2,4,6-Trinitrophenyl hapten (TNP) - Keyhole Limpet Hemocyanin (KLH)-primed B cells cocultured with OVA-primed CD4(+) T cells from OVA-immunized VSIG4 KO mice in the presence of TNP-OVA showed enhanced isotype switching to IgG subclasses compared to those cocultured with cells isolated from OVA-immunized wild-type (WT) mice. IP3K Inhibitor V-set and immunoglobulin domain containing 4 Mus musculus