Title : Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner.

Pub. Date : 2015 Jul

PMID : 25926433






1 Functional Relationships(s)
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1 The objective of this study is to investigate whether an agonist of FXR, 3-(2,6-dichlorophenyl)-4-(3"-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole (GW4064), alters CYP2D6 expression and activity. 3-(2,6-dichlorophenyl)-4-(3"-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole nuclear receptor subfamily 1, group H, member 4 Mus musculus