Pub. Date : 2015 Nov
PMID : 25925501
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meta-analysis of the RCTs showed that metformin had statistically significant effects on pregnancy-induced hypertension [PIH; risk ratio (RR) 0.54; 95% confidence interval (CI) 0.31, 0.91]. | Metformin | pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) | Homo sapiens |
| 2 | Our analyses suggest that there is no clinically relevant difference in efficacy or safety between metformin and insulin; however, metformin may be a good choice for GDM because of the lower risk of PIH. | Metformin | pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) | Homo sapiens |
| 3 | The advantages of metformin in terms of glycaemic control, PIH incidence and gestational age at birth are unclear, and should be verified in further trials. | Metformin | pregnancy-induced hypertension (pre-eclampsia, eclampsia, toxemia of pregnancy included) | Homo sapiens |