Title : Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S.

Pub. Date : 2015

PMID : 25902334






1 Functional Relationships(s)
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1 In many different human cancers, one of the HRAS, NRAS, or KRAS genes in the RAS family of small GTPases acquires an oncogenic mutation that renders the encoded protein constitutively GTP-bound and thereby active, which is well established to promote tumorigenesis. Guanosine Triphosphate HRas proto-oncogene, GTPase Homo sapiens