Title : The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis.

Pub. Date : 2015

PMID : 25896587






3 Functional Relationships(s)
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1 The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis. Quercetin tumor protein p53 Homo sapiens
2 RESULTS: miR-34a was up-regulated in HepG2 cells treated by quercetin exhibiting wild-type p53. Quercetin tumor protein p53 Homo sapiens
3 When inhibiting the miR-34a, the sensitivity of the cells to quercetin decreased and the expression of the SIRT1 was up-regulated, but the acetylation of p53 and the expression of some genes related to p53 down-regulated. Quercetin tumor protein p53 Homo sapiens