Title : Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-dependent upregulation of glutathione synthesis.

Pub. Date : 2015 Sep

PMID : 25880604






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 IL-1beta treatment prevented the increase in reactive oxygen species produced in astrocytes following tBOOH exposure. tert-Butylhydroperoxide interleukin 1 beta Mus musculus
2 Additionally, the toxicity induced by tBOOH or FeSO4 exposure was significantly attenuated following treatment with IL-1beta, an effect reversed by concomitant exposure to l-buthionine-S,R-sulfoximine (BSO), which prevented the IL-1beta-mediated rise in GSH production. tert-Butylhydroperoxide interleukin 1 beta Mus musculus
3 Additionally, the toxicity induced by tBOOH or FeSO4 exposure was significantly attenuated following treatment with IL-1beta, an effect reversed by concomitant exposure to l-buthionine-S,R-sulfoximine (BSO), which prevented the IL-1beta-mediated rise in GSH production. tert-Butylhydroperoxide interleukin 1 beta Mus musculus