Title : 3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling.

Pub. Date : 2015 Jun

PMID : 25878061






2 Functional Relationships(s)
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1 Interestingly, in ADRA2A/TAAR1 hetero-oligomers, application of NorEpi resulted in uncoupling of the Gi/o signaling pathway, but it did not affect MAPK activation. Norepinephrine trace amine-associated receptor 1 Mus musculus
2 Moreover, in ADRA2A/TAAR1 hetero-oligomers, the capacity of NorEpi to stimulate Gi/o signaling is reduced by co-stimulation with 3-T1AM. Norepinephrine trace amine-associated receptor 1 Mus musculus