Title : [Jaridonin induces apoptosis in human esophageal cancer cells by depleting GSH and inducing DNA damage].

Pub. Date : 2015 Jan

PMID : 25877312






3 Functional Relationships(s)
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1 Jaridonin resulted in extensive p53 up-regulation in the EC-1 cells. jaridonin tumor protein p53 Homo sapiens
2 More importantly, the p53 up-regulation occurred as early as 2 h after Jaridonin incubation, and in a time-dependent manner (P < 0.05). jaridonin tumor protein p53 Homo sapiens
3 p53 siRNA transfection inhibited apoptosis in the EC-1 cells, and the Jaridonin-induced apoptosis rate was reduced from 38.5% to 8.8%. jaridonin tumor protein p53 Homo sapiens