Pub. Date : 2015 Apr 13
PMID : 25869667
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By comparing the properties of wild-type K14 with a completely cysteine-free variant thereof, we found that K14-dependent disulfide bonding limited filament elongation during polymerization in vitro but was necessary for the genesis of a perinuclear-concentrated network of keratin filaments, normal keratin cycling, and the sessile behavior of the nucleus and whole cell in keratinocytes studied by live imaging. | Cysteine | keratin 14 | Mus musculus |
| 2 | Many of these phenotypes were rescued when analyzing a K14 variant harboring a single Cys residue at position 367. | Cysteine | keratin 14 | Mus musculus |