Title : ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

Pub. Date : 2015 Oct 15

PMID : 25868794






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 All EZH2 inhibitors are transported by P-gp and BCRP, although in vitro the transporter affinity of GSK126 was obscured by very low membrane permeability. GSK-2816126 phosphoglycolate phosphatase Mus musculus