Title : Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells.

Pub. Date : 2015

PMID : 25837881






6 Functional Relationships(s)
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1 Akt signaling is associated with the berberine-induced apoptosis of human gastric cancer cells. Berberine AKT serine/threonine kinase 1 Homo sapiens
2 In our further studies, the results demonstrated that Akt-related mitochondrial pathway may partly involve in the berberine-induced apoptosis in human gastric cancer cells. Berberine AKT serine/threonine kinase 1 Homo sapiens
3 Moreover, berberine inhibited the Akt/mTOR/p70S6/S6 pathway in berberine-treated BGC-823 cells. Berberine AKT serine/threonine kinase 1 Homo sapiens
4 Moreover, berberine inhibited the Akt/mTOR/p70S6/S6 pathway in berberine-treated BGC-823 cells. Berberine AKT serine/threonine kinase 1 Homo sapiens
5 Thus, our findings reveal that the underlying mechanism that Akt signaling may contribute to berberine-induced cell apoptosis in gastric cancer cells and might represent an important molecular basis for berberine to act as an anticancer agent. Berberine AKT serine/threonine kinase 1 Homo sapiens
6 Thus, our findings reveal that the underlying mechanism that Akt signaling may contribute to berberine-induced cell apoptosis in gastric cancer cells and might represent an important molecular basis for berberine to act as an anticancer agent. Berberine AKT serine/threonine kinase 1 Homo sapiens