Title : Ganoderic acid B's influence towards the therapeutic window of trifluoperazine (TFP).

Pub. Date : 2015 Mar

PMID : 25834543






2 Functional Relationships(s)
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1 Given that the glucuronidation reaction of TFP is the probe reaction of UGT1A4, the data obtained from the present study also indicated the potential influence of Ganoderic acid-containing herbs towards the therapeutic window of drugs mainly undergoing UGT1A4-mediated metabolism. ganoderic acid UDP glucuronosyltransferase family 1 member A4 Homo sapiens
2 Given that the glucuronidation reaction of TFP is the probe reaction of UGT1A4, the data obtained from the present study also indicated the potential influence of Ganoderic acid-containing herbs towards the therapeutic window of drugs mainly undergoing UGT1A4-mediated metabolism. ganoderic acid UDP glucuronosyltransferase family 1 member A4 Homo sapiens