Title : Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine.

Pub. Date : 2015 Apr 10

PMID : 25826076






1 Functional Relationships(s)
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1 Using a reporter knock-in construct, chemical compounds were screened, and Wee1 kinase inhibitor was identified as upregulators of miR122 transcription, which increased the sensitivity of the cells to sorafenib. Sorafenib WEE 1 homolog 1 (S. pombe) Mus musculus