Pub. Date : 2015 May
PMID : 25823563
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | These observations collectively strongly suggest that both endoplasmic reticulum stress-mediated calcium release and Bax targeting might be altering mitochondrion membrane potential which in turn could induce secondary apoptotic signals; subsequently, endoplasmic reticulum stress can also lead to nuclear localization of Nuclear factor-kappaB (NF-kappaB) which in turn favors p53 mediated apoptotic signals. | Calcium | tumor protein p53 | Homo sapiens |