Title : Platelet-derived miR-103b as a novel biomarker for the early diagnosis of type 2 diabetes.

Pub. Date : 2015 Oct

PMID : 25820527






4 Functional Relationships(s)
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1 The objective of this study was to test the hypothesis that platelet-derived miR-103b (miR-103-as), which regulates SFRP4, might be a novel biomarker for the early diagnosis of DM2. mir-103b secreted frizzled related protein 4 Homo sapiens
2 Furthermore, SFRP4 mRNA and protein levels were down-regulated by a miR-103b mimic but were up-regulated by a miR-103b inhibitor. mir-103b secreted frizzled related protein 4 Homo sapiens
3 CONCLUSIONS: The results suggest that platelet-derived miR-103b could negatively regulate the expression of SFRP4 mRNA/protein in pre-DM2, indicating that miR-103b could be a novel biomarker for the early diagnosis of DM2. mir-103b secreted frizzled related protein 4 Homo sapiens
4 CONCLUSIONS: The results suggest that platelet-derived miR-103b could negatively regulate the expression of SFRP4 mRNA/protein in pre-DM2, indicating that miR-103b could be a novel biomarker for the early diagnosis of DM2. mir-103b secreted frizzled related protein 4 Homo sapiens