Title : STAT1-mediated down-regulation of Bcl-2 expression is involved in IFN-γ/TNF-α-induced apoptosis in NIT-1 cells.

Pub. Date : 2015

PMID : 25811609






1 Functional Relationships(s)
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1 Knockdown of STAT-1 gene expression by siRNA or inhibition of STAT-1 activation with fludarabine reversed Bcl-2 down-expression and led to a significant decrease in apoptosis in TNF-alpha- and IFN-gamma-treated NIT-1 cells. fludarabine signal transducer and activator of transcription 1 Mus musculus