Title : The loss of Tm7sf gene accelerates skin papilloma formation in mice.

Pub. Date : 2015 Mar 25

PMID : 25804527






2 Functional Relationships(s)
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1 Cholesterol sulfate, one of the major players in skin permeability, was doubled by TPA treatment in the skin of wild-type animals but this response was lost in Tm7sf2(-/-) mice. cholesteryl sulfate transmembrane 7 superfamily member 2 Mus musculus
2 In conclusion, the loss of Tm7sf2 alters the expression of proteins involved in epidermal differentiation by reducing the levels of cholesterol sulfate. cholesteryl sulfate transmembrane 7 superfamily member 2 Mus musculus