Title : Phosphatidylinositol-3,4,5-trisphosphate stimulates Ca(2+) elevation and Akt phosphorylation to constitute a major mechanism of thromboxane A2 formation in human platelets.

Pub. Date : 2015 Jul

PMID : 25797048






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 DiC8-PIP3 induced the phosphorylation of Akt-Ser(473) which was reduced by the Akt inhibitor IV, wortmannin and EGTA (suggesting a dependence on Ca(2+) entry). Egtazic Acid AKT serine/threonine kinase 1 Homo sapiens