Title : GD3- and O-acetylated GD3-gangliosides in the GM2 synthase-deficient mouse brain and their immunohistochemical localization.

Pub. Date : 2006 Sep

PMID : 25792782






1 Functional Relationships(s)
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1 Gangliosides in the brain of the knockout mouse deficient in the activity of beta1,4 N-acetylgalactosaminyl transferase (beta1,4 GalNAc-T)(GM2 synthase) consisted of nearly exclusively of GM3- and GD3-gangliosides as expected from the known substrate specificity of the enzyme and in confirmation of the initial reports from two laboratories that generated the mutant mouse experimentally. Gangliosides granulocyte macrophage antigen 3 Mus musculus