Title : Mechanism of the inhibitory action of dopamine and somatostatin on prolactin secretion from human lactotrophs in culture.

Pub. Date : 1985 Mar

PMID : 2579087






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 When the cells were incubated in low calcium medium, PRL secretion was significantly inhibited. Calcium prolactin Homo sapiens
2 These results suggest that an increase in cytosol calcium caused by either mobilization from intracellular calcium pools or influx from the extracellular compartment and intracellular cAMP accumulation may be involved in the mechanism of PRL secretion from human lactotrophs, and dopamine and somatostatin may influence these two messengers to suppress PRL secretion. Calcium prolactin Homo sapiens
3 These results suggest that an increase in cytosol calcium caused by either mobilization from intracellular calcium pools or influx from the extracellular compartment and intracellular cAMP accumulation may be involved in the mechanism of PRL secretion from human lactotrophs, and dopamine and somatostatin may influence these two messengers to suppress PRL secretion. Calcium prolactin Homo sapiens