Pub. Date : 2015 Mar 30
PMID : 25788262
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |
2 | Overexpression of Skp2, or siRNA knockdown of p21Cip1, p27Kip1, or p53 blocked suppressive effect of CAPE treatment. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |
3 | Our finding suggested that CAPE treatment induced cell cycle arrest and growth inhibition in CRPC cells via regulation of Skp2, p53, p21Cip1, and p27Kip1. | caffeic acid phenethyl ester | tumor protein p53 | Homo sapiens |