Title : Morphine-Induced Constipation Develops With Increased Aquaporin-3 Expression in the Colon via Increased Serotonin Secretion.

Pub. Date : 2015 Jun

PMID : 25766885






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Aquaporin-3 (AQP3) is a water channel that is predominantly expressed in the colon, where it plays a critical role in the regulation of fecal water content. Water aquaporin 3 (Gill blood group) Homo sapiens
2 Aquaporin-3 (AQP3) is a water channel that is predominantly expressed in the colon, where it plays a critical role in the regulation of fecal water content. Water aquaporin 3 (Gill blood group) Homo sapiens
3 Aquaporin-3 (AQP3) is a water channel that is predominantly expressed in the colon, where it plays a critical role in the regulation of fecal water content. Water aquaporin 3 (Gill blood group) Homo sapiens
4 Aquaporin-3 (AQP3) is a water channel that is predominantly expressed in the colon, where it plays a critical role in the regulation of fecal water content. Water aquaporin 3 (Gill blood group) Homo sapiens
5 The results suggest that morphine increases the AQP3 expression level in the colon, which promotes water absorption from the luminal side to the vascular side and causes constipation. Water aquaporin 3 (Gill blood group) Homo sapiens