Title : Endothelium-dependent regulatory mechanisms in human coronary bypass grafts: possible clinical implications.

Pub. Date : 1989

PMID : 2575830






1 Functional Relationships(s)
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1 In mammary arteries, acetylcholine, thrombin, adenosine diphosphate, histamine and the calcium ionophore A23187 evoked endothelium-dependent relaxations blocked by hemoglobin or methylene blue, but not by cyclooxygenase inhibitors delineating EDRF as the mediator; in vascular smooth muscle cells, this was associated with a rise in intracellular cyclic GMP. Histamine 5'-nucleotidase, cytosolic II Homo sapiens